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1.
Rev. panam. infectol ; 16(1): 62-66, 2014. ilus
Article in Portuguese | LILACS, SES-SP | ID: biblio-1067140

ABSTRACT

Relatamos a ocorrência da Síndrome Inflamatória da RecuperaçãoImune (IRIS), após reversão de agranulocitose, induzida por poliquimioterapia,em paciente do sexo feminino acometida por hanseníasedimorfa-virchowiana. Propomos que em todos os pacientes submetidosà poliquimioterapia para hanseníase sejam efetuados periodicamenteexames laboratoriais que possam identificar precocementedistúrbios hematológicos graves


We report the occurrence of Immune Reconstitution InflammatorySyndrome (IRIS) after reversal of agranulocytosis provoked by drugor drugs used in the treatment of leprosy. After suspension of thedrugs under suspicion and the recovery of the hematologic disturbanceand as consequence the restoration of the immune conditionwe started an alternate treatment for Hansen’s disease. Takingthis case as an example, we propose that all patients with leprosyand under treatment with drugs such as dapsone and/ or rifampicinshould have a periodical hemogram to identify premature hematologicanomalies.


Subject(s)
Female , Humans , Adult , Agranulocytosis , Leprosy, Multibacillary , Immune Reconstitution Inflammatory Syndrome , Clofazimine , Dapsone , Drug Therapy, Combination , Case Reports , Rifampin
2.
Braz. j. infect. dis ; 13(2): 158-160, Apr. 2009.
Article in English | LILACS | ID: lil-538225

ABSTRACT

Multidrug therapy (WHO/MDT) in multibacillary leprosy consists of treatment with rifampicin, dapsone andclofazimine. However, adverse effects can cause the patient to abandon treatment. We report on a patient whopresented agranulocytosis and hemolytic anemia associated with this treatment regime. We also examined theimportance of laboratory exams for diagnosis and follow-up of the patient, and for early detection of adverse effects, with a view to improving adhesion to treatment and contributing to the eradication of Hansen’s disease as a public health issue.


Subject(s)
Adult , Female , Humans , Agranulocytosis/chemically induced , Anemia, Hemolytic/chemically induced , Leprostatic Agents/adverse effects , Clofazimine/adverse effects , Dapsone/adverse effects , Drug Therapy, Combination/adverse effects , Leprosy/drug therapy , Rifampin/adverse effects
3.
Rev. bras. ciênc. saúde ; 8(2): 199-206, maio-ago. 2004.
Article in Portuguese | LILACS | ID: lil-406830

ABSTRACT

Os autores apresentam uma série clínica de vinte e dois pacientes adultos infectados pelo Stafilococcus Aureus meticilino resistente (MRSA), de 1997 a 1999, observados do Hospital Universitário Lauro Wanderley (HULW) em João Pessoa - Paraíba - Brasil. Além disso, enfatizam o intervalo médio entre a admissão do paciente e o diagnóstico da infecção por MRSA, quantificam a incidência de casos, a distribuição por sexo e por faixa etária, determinam o índice de mortalidade e abordam sobre a dificuldade atual no manuseio destas cepas meticilino-resistente


Subject(s)
Humans , Male , Female , Adult , Cross Infection/diagnosis , Methicillin Resistance , Therapeutics
5.
CCS ; 13(4): 57-9, out.-dez. 1994. ilus
Article in Portuguese | LILACS | ID: lil-200953

ABSTRACT

Relata-se um caso de ofidismo em uma vítima de 53 anos de idade, procedente de Mamanguape-PB, picada por jararaca (Bothrops erythromelas) no pé e que se estendeu com lesöes externas equimóticas comprometendo todo o membros inferiores e regiäo dorsal. Tratada com soro antiofídico e antibióticos, teve alta após 14 dias de hospitalizaçäo


Subject(s)
Male , Middle Aged , Humans , Antivenins/therapeutic use , Bothrops , Snake Bites/therapy
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